Revista chilena de cardiología
versión On-line ISSN 0718-8560
GAJARDO, Luis et al. Differences in coronary atherosclerosis assessed with the Gensini score between men and women with type 2 Diabetes. Rev Chil Cardiol [online]. 2012, vol.31, n.2, pp. 96-101. ISSN 0718-8560. http://dx.doi.org/10.4067/S0718-85602012000200002.
Diabetic women have higher morbidity and mortality associated with ischemic coronary events than diabetic men, but the extension of coronary artery disease in both groups is less well established. Aim: to compare the extension, magnitude and severity of coronary atherosclerosis between men and women with type 2 diabetes mellitus. Method: 162 consecutive diabetic patients with suspected coronary atherosclerosis studied by coronary angiography were included. The magnitude of atherosclerosis was quantified using the Gensini Score. Results: The average age was 64.8 years. Ninety-four patients were women (58.0%). Diabetes was present for 152 ± 90.0 months for women and 120 ± 99.4 months for men (p <0.05). Women had a higher body mass index (30.5 ± 5.1) than men (28.5 ± 5.2, p<0.05). The presence of significant coronary atherosclerosis in the entire diabetic population was of 61.7%: 76.5% in men and 51.5% in women (OR 1.5). The mean number of atherosclerotic plaques was 195 in 68 men (2.86 plaques/patient) and 168 in 94 women (1.78 plaques/patient, p=0.0043). Significant atherosclerosis in 1, 2 and 3 vessels was observed in 7.4%, 17.6% and 51.5% of men, respectively, versus 12.8%, 10.6% and 27.7% in women (p<0.0002). The magnitude of coronary disease measured by Gensini Score was 69.4 + 66.7 in men versus 35.6 ± 47.3 in women (p<0.005). Conclusion: Men with diabetes have greater extension, magnitude and severity of coronary atherosclerosis than diabetic women.
Palabras llave : Coronary angiography; Diabetes melli-tus; Atherosclerosis.