Revista chilena de cardiología
versión On-line ISSN 0718-8560
MALUENDA, Gabriel et al. Percutaneous aortic balloon valvuloplasty as a bridge to aortic valve replacement in severe aortic stenosis. Rev Chil Cardiol [online]. 2012, vol.31, n.1, pp. 11-17. ISSN 0718-8560. http://dx.doi.org/10.4067/S0718-85602012000100001.
Background: the recent introduction of percutaneous aortic valve replacement (PAVR) has become a stimulus to perform percutaneous aortic balloon valvu-loplasty (PABV) in patients with severe symptomatic aortic stenosis (AS) as a bridge to valve replacement (AVR) Aim: to determine success rates and clinical results of PABV alone vs those obtained with PABV followed by either surgical or percutaneous AVR. Method: 472 patients with severe AS underwent a total of 538 PABV procedures. 378 (82%) were treated with PABV alone (Group I). In Group II, 85 patients (18%) had PABV followed by either PAVR (n=65) or surgical AVR (n=20). A successful PABV was defined as >40% reduction in mean aortic valve pressure gradient or >40% increase in aortic valve area Results: Groups I and II were comparable regarding age (81.7±8.3 vs. 83.2±10.9 years, p=0.18), STS score (13.1±6.2 vs. 12.4±6.4, p=0.4) and Logistic Euroscore (45.4±22.3 vs. 46.9±21.8, p=0.43). Mean increase in AVA was 0.39±0.25 cm2 in Group I and 0.42±0.26 cm2 in Group II (p=0.33). Mean aortic valve pressure gradient decreased 24.1±13.1 mmHg in Group I and 27 ±1.8 mmHg in Group II (p=0.06). PABV was not successful in 81 patients (15%). As expected, repeated PABV was the main predictor for failure (HR 4.34[95%, CI 2.2-8.3], p<0.001). Midterm mortality rate was 55.2% (214 patients) in Group I and 22.3% (19 patients) in Group II (p<0.001). Intra-pro-cedure mortality was identical in both Groups (2%). Stroke occurred in 2.3% of patients in Group I vs 1.6% in Group II. Conclusion: In high risk patients with severe AS and temporary contraindication for percutaneous or surgical AVR, PABV may be used as a bridge for intervention with good midterm results.