Revista de otorrinolaringología y cirugía de cabeza y cuello
versión On-line ISSN 0718-4816
HERRERA J, María José; GAJARDO O, Pilar; BEDOYA M, Juliana y GONZALEZ G, Claudia. Toll like receptors role in the allergic rhinitis. Rev. Otorrinolaringol. Cir. Cabeza Cuello [online]. 2010, vol.70, n.1, pp. 71-80. ISSN 0718-4816. doi: 10.4067/S0718-48162010000100012.
Allergic rhinitis (AR) affects about six hundred million people worldwide and is now considered the most prevalent recurrent disease. The pathogenesis of AR involves a complex network of cellular and humeral mediators involved in the Th2 immune profile. Together with the adaptive immune system, components of innate immunity have shown to play an important role in allergic diseases such as atopic dermatitis and bronchial asthma. The present review describes the role of Toll-like receptors in allergic rhinitis. We discuss the importance of the receptors expression, function and modulation in this disease.
Palabras clave : Allergic rhinitis; toll like receptors; immunology.