Revista chilena de cirugía
versión On-line ISSN 0718-4026
YANEZ M, RICARDO et al. Surgical treatment in hepatocellular carcinoma: Preliminary experience. Rev Chil Cir [online]. 2010, vol.62, n.1, pp.22-26. ISSN 0718-4026. http://dx.doi.org/10.4067/S0718-40262010000100004.
Background: The hepatocellular carcinoma (HCC) is the main primary liver tumour and is a major health problem worldwide, it is the fifth most common cáncer in the world, as only 10% to 20% are resectable and the natural progression of the disease presents an ominous prognosis with lower overall survival of less than nine months. The aim of this paper is to analyze the results of the surgical alternatives of HCC in our center. Patients and Methods: Analysis of the prospective database of all patients with HCC under-going surgical treatment between 2003 and 2008 in terms of surgical technique (liver transplantation, liver resection and radiofrequency ablation surgery), surgical margins, complications, tumour recurrence and survival. Results: The series was 38 patients, 23 women, median age 65 years (41-82 years), were early and late complications in six patients (15.8%) respectively. The cumulative survival of all patients undergoing to surgical treatment was 86%, 76% and 65% foryear 1, 2, 3 postoperative respectively. According technique: 14 patients underwent liver transplantation, liver resection in eight patients, 15 patients with radiofrequency ablation and a patient with resection and surgical radiofrequency. Discussion: The surgical treatment of HCC in our series presented promising results in terms of survival globally and for each surgical option used. Thus the surgical treatment of HCC is beneficial in selected patients in terms of surgical complications and survival.
Palabras clave : Hepatocellular carcinoma; liver transplantation; liver resection; radiofrequency ablation.