Revista chilena de cirugía
versión On-line ISSN 0718-4026
HUIDOBRO M, Patricio et al. Clinical utility of initial dissemination study an patients with stage I or II breast cancer I. Rev Chil Cir [online]. 2006, vol.58, n.2, pp. 89-96. ISSN 0718-4026. http://dx.doi.org/10.4067/S0718-40262006000200004.
Background: The study of tumor dissemination in stages I and II of breast cancer is not justified. However there may be a group of patients in these stages that has a higher risk of dissemination Aim: To study the yield and clinical usefulness of baseline staging tests in patients with breast cancer. Material and methods: A retrospective analysis of 616 patients with breast cancer. Among these, 374 patients were in stages I and II and were further divided according to the presence or absence of palpable axillary lymph nodes. Global clinical utility of staging tests was defined as basal positive tests plus basal negative exams that served as comparison for new abnormal tests, that detected the presence of metastases during follow up. Results: Two hundred and four patients in stage I and II had palpable axillary lymph nodes and 13 had metastases (6%). In 170 patients, lymph nodes were not detected and four had metastases (2.3%, p=0.08 as compared with the group with lymph nodes). During a follow up ranging from 6 months to 23 years, 50 patients with palpable lymph nodes and 25 without palpable lymph nodes, developed metastases (p=0.02). The global clinical utility for all the baseline staging tests was 24% (53/217) in patients with palpable lymph nodes and 14,4% (25/174) in patients without lymph nodes (p=0,02). Additionally, in 41 of 204 patients with lymph nodes (20%), abdominal ultrasound showed colelithiasis. Conclusions: Baseline staging tests are of clinical utility in patients with breast cancer an suspicious axillary nodes
Palabras clave : Baseline staging tests; clinical utility; protocols; axillary nodes.