Journal of the Chilean Chemical Society
versão ISSN 0717-9707
XIE, MINHAO et al. HIGHLY EFFICIENT AND VERSATILE ACETYLATION OF ALCOHOLS, PHENOLS AND AMINES CATALYZED BY METHYLENEDIPHOSPHONIC ACID (MDP) UNDER SOLVENT-FREE CONDITIONS. J. Chil. Chem. Soc. [online]. 2011, vol.56, n.4, pp. 884-886. ISSN 0717-9707. doi: 10.4067/S0717-97072011000400013.
Methylenediphosphonic Acid (MDP) was found to be a simple, cheap and reusable heterogeneous catalyst for the acetylation of structurally diverse alcohols, phenols and amines with acetic anhydride under solvent-free conditions at room temperature. This method showed preferential selectivity for the acetylation of the amino group in the presence of hydroxyl group. The method is very mild and the yields were in excellent.
Palavras-chave : Bisphosphonic acid; MDP; Solvent-free; Acetylation.