Resumen

MOSADDEGH, ELAHEH; HASSANKHANI, ASADOLLAH  y  BAGHIZADEH, AMIN. CELLULOSE SULFURIC ACID AS A NEW, BIODEGRADABLE AND ENVIRONMENTALLY FRIENDLY BIO-POLYMER FOR SYNTHESIS OF 4,4'-(ARYLMETHYLENE)BIS(3-METHYL-1-PHENYL-1H-PYRAZOL-5-OLS). J. Chil. Chem. Soc. [online]. 2010, vol.55, n.4, pp. 419-420. ISSN 0717-9707.  doi: 10.4067/S0717-97072010000400001.

The one-pot multicomponent synthesis of 4,4'-arylmethylene-bis(3-methyl-1-phenyl-1H-pyrazol-5-ol) was performed effectively by tandem Knoevenagel-Michael reaction of aryl aldehydes and 5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one in the presence of a catalytic amount of cellulose sulfuric acid as an environmentally friendly biopolymer-based solid acid catalyst at reflux conditions. All of obtained compounds were characterized by FT IR, ¹H and ¹³C NMR. This new methodology is of interest due to minimizing the cost operational hazards and environmental pollution, high yields, short reaction time, cost effective and simple work-up.

Palabras clave : Cellulose sulfuric acid; biopolymer; 4,4'-(arylmethylene)bis(3-methyl-1-phenyl-1H-pyrazol-5-ols); 5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one; environmentally friendly.