SciELO - Scientific Electronic Library Online

 
vol.54 número1MICROWAVE-ASSISTED SYNTHESIS OF BENZOFURAN ANALOGS OF FENAMATES AS NON STEROIDAL ANTI-INFLAMMATORY AGENTSSYNERGISTIC EFFECT OF CALOTROPIS PLANT IN CONTROLLING CORROSION OF MILD STEEL IN BASIC SOLUTION índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Articulo

Indicadores

  • No hay articulos citadosCitado por SciELO

Links relacionados

  • No hay articulos similaresSimilares en SciELO

Journal of the Chilean Chemical Society

versión On-line ISSN 0717-9707

Resumen

LIU, PENGFEI et al. IDENTIFICATION OF KURARINONE BY LC/MS AND INVESTIGATION OF ITS THERMAL STABILITY. J. Chil. Chem. Soc. [online]. 2009, vol.54, n.1, pp. 80-82. ISSN 0717-9707.  http://dx.doi.org/10.4067/S0717-97072009000100019.

A herbal ingredient kurannone (7, 2', 4,-trihydroxy-8-lavandulyl-5-methoxy flavanone) was isolated from the roots of sophoraflavescens Ait by ultrasonic extraction, which is one of tradicional Chinese medicine (TCM) materials. A reliable high performance liquid chromatography with mass spectrometry (HPLC-MS) method was used for determination of kurarinone. C18 column (150x4.6 mm, 5 µm) and methanol-water mobile phase (70:30, by volume) were used in the chromatographic separation of active components from the herb. HPLC-ESI-MS (UV, 288 nm; m/z, 437.5 [M-H]-) was adopted for kurarinone identification. Kurarinone with purity of 95.5% was obtained by silica gel column foUowed by reverse-phase column chromatography. The thermal stability of kurarinone was investigated, which illustrates that kurarinone was stable below 25 °C in 48 h, but a degradation of 25.54% was observed at 80 °C for 2 h.

Palabras llave : Sophoraflavescens Ait; Leguminosae; Flavonoids; Kurarinone; HPLC-ESI-MS; Ultrasonic extraction; Thermal stability.

        · texto en Inglés     · pdf en Inglés