Journal of the Chilean Chemical Society
versión On-line ISSN 0717-9707
NEIRA-CARRILLO, ANDRÓNICO; RETUERT, JAIME; MARTINEZ, FRANCISCO y ARIAS, JOSÉ LUIS. EFFECT OF CROSSLINKED CHITOSAN AS A CONSTRAINED VOLUME ON THE IN VITRO CALCIUM CARBONATE CRYSTALLIZATION. J. Chil. Chem. Soc. [online]. 2008, vol.53, n.1, pp. 1367-1372. ISSN 0717-9707. doi: 10.4067/S0717-97072008000100009.
The present work deals with the effect of the constrained volume given by crosslinked chitosan (CHI) as a sphere on the in vitro CaC03 crystallization. Crosslinked CHI was obtained with formaldehyde (FA), glutaraldehyde (GA), epichlorhydrine (EPCH) and poly (propylene glycol) diglycidyl ether (PPDGE) as crosslinking agents. Determination of swelling percentage (%) of the crosslinked CHI spheres was carried out in TRIS buffer at pH 9. Spheres of high molecular weight were prepared using drops of CHI solution on NaOH. In vitro CaC03 crystallization using gas-diffusion method was done. In addition, a synthetically sulphonated containing polymethylsiloxane (S-PMS) was used as modifying additive on the CaC03 crystals growth in a confined space of CHI. The degree of the crosslinking altered the diffusion of C02 gas through the CHI spheres during the CaC03 crystallization resulting in different and specific crystals morphologies
Palabras clave : chitosan; crosslinking agents; gas-diffusion method; crystallization and calcite crystals.