Abstract

ISSA, Joáo Paulo Mardegan et al. Optical Densitometry Study of the Newly Formed Bone Using rhBMP-2 in Wistar Rat Mandibles. Int. J. Morphol. [online]. 2007, vol.25, n.2, pp. 347-352. ISSN 0717-9502.  doi: 10.4067/S0717-95022007000200018.

The purpose of this study was to evaluate the efficacy of monoolein gel as a carrier for rhBMP-2 in the healing bone process of critical bone defects created in Wistar rats mandibles using digitalized radiographic method to analyze this process. In the group 1, the rhBMP-2 was dissolved in aqueous solution and in the group 2, the rhBMP-2 was combined with monoolein gel as a carrier. The results showed that in both of groups it was found efficient bone repair, with a great optical density in the group that the rhBMP-2 was combined with the monoolein gel, but without statistical difference between them

Keywords : Optical densitometry; rhBMP-2; Monoolein; Bone defects.