International Journal of Morphology
versión On-line ISSN 0717-9502
ARAUJO, Eduardo José de Almeida; SANT'ANA, Débora de Mello Gonçales; MOLINARI, Sonia Lucy y MIRANDA NETO, Marcílio Hübner de. Quantitative Study of the Myenteric Plexus of the Descending Colon of Young Rats Subjected to Intense Protein Deficiency . Int. J. Morphol. [online]. 2006, vol.24, n.4, pp.591-597. ISSN 0717-9502. http://dx.doi.org/10.4067/S0717-95022006000500013.
We studied the effects of a severely hypoproteic diet on the quantitative aspects of the myenteric plexus of the descending colon of young rats. Eighteen rats were divided into two groups, one of them being fed with a chow having 26% protein (control) and the other with a chow having 4% protein, balanced for minerals and vitamins, during 12 weeks. The whole-mounts of the descending colon had their myenteric neurons stained either with Giemsa or NADPH diaphorase. The rats from the experimental group had deficits of body weight (54.23%) and area of the descending colon (48.14%); additionally, we observed that there was no alteration in the total number of neurons of the colon, but a decrease in the number of NADPH-diaphorase positive neurons (37.80%). The implications of these results concerning the priority that some cellular types may have when nutrients are less available are discussed
Palabras clave : Myenteric plexus; Protein-energy; Malnutrition (PEM); Descending colon.