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Revista chilena de neuro-psiquiatría

versión On-line ISSN 0717-9227


POBLETE P, Tomás; DONOSO C, María Teresa  y  HOLZER M, Fredy. Description of patients that underwent brain metastases surgery in Asenjo Neurosurgery Institute (INCA). Rev. chil. neuro-psiquiatr. [online]. 2008, vol.46, n.2, pp.101-106. ISSN 0717-9227.

Background: Brain metastases are an increasing cause ofmorbimortality in patients with cáncer. There are few national reports about surgical treatment of these patients. Objective: Description of patients that underwent surgical metastases surgery, survival and functionality. Methods: Retrospective study including all patients treated with surgery between 2003 and 2006 in Asenjo Neurosurgery Institute, which histological diagnosis confirmed brain metástasis. After surgery, follow up was made by telephone to determine survival and functional impairment. Results: A total offifty patients underwent surgery. The most frequent primary tumor was lungwith 28%. The distribution of lesions in cerebrum, cerebellum and brainstem was: 74%, 22% and 4% respectively Telephone contad after surgery was successful in 17 patients, ofwhom 10 received postoperative radiotherapy, 4 didrít receive any other treatment and 3 didntprovide information. The overall rate of survival in the 17 patients was 45,7 weeks. When the postoperative radiotherapy subgroup was compared with only surgery subgroup, the mean survival was 46,7 and 31 weeks respectively, with no significant difference (p > 0,2). Functional impairment increased from 4 patients in preoperatory to 8 after surgery. Conclusions: In this group, the combination of surgery plus radiotherapy increased the survival in 3,9 months. The increase in functional impairment after surgery can be explained because of the primary tumor progression. An appropriate selection of patients for surgery would result in an increase in the number of operated patients, and the experience in the management for these patients.

Palabras clave : Brain neoplasm metastasis; surgery; survival.

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