Abstract

YAMAMOTO C, Masami et al. ALTA PREVALENCIA DE IGG ANTI CITOMEGALOVIRUS EN 583 EMBARAZOS: HOSPITAL PADRE HURTADO. Rev. chil. obstet. ginecol. [online]. 2009, vol.74, n.2, pp. 102-106. ISSN 0717-7526.  http://dx.doi.org/10.4067/S0717-75262009000200006.

Background: Cytomegalovirus is the most frequent congenital infection, affecting 1% of the population in developed countries, and the leading cause of deafness and brain development abnormalities in children. Recent studies have demonstrated that seropositivity do not avoid reinfection and congenital disease. Objective: To study the seroprevalence in 583 pregnant women at delivery at Padre Hurtado Hospital, during 2006. Methods: Prospective, observational study, in which maternal blood at delivery was studied for the presence of anti CMV IgG. Results: There was 95% seroprevalence, without any case of symptomatic infection. Conclusion: The high prevalence supports that most of the cases of congenital disease would occur in seropositive women, supporting that reinfection is the main way of neonatal compromise. This supports that a study with direct detection in liveborns would be suitable to reveal the impact of cytomegalovirus in our population and not that of seroconversión.

Keywords : Congenital cytomegalovirus; screening; serology; prevalence.