Revista chilena de obstetricia y ginecología
versión On-line ISSN 0717-7526
CHEVIAKOFF Z, Sergio; CARMONA G, Sergio y LAHSEN M DE LA P, Rodolfo. ESTUDIOS DE VARIABLES CLÍNICAS Y METABÓLICAS EN MUJERES CON HIPERANDROGENISMO CLÍNICO. Rev. chil. obstet. ginecol. [online]. 2004, vol.69, n.1, pp. 39-43. ISSN 0717-7526. doi: 10.4067/S0717-75262004000100008.
Policystic ovary disease is the most frequent presentation of hyperandrogenism in women and its prevalence varies between 4 and 7%. It is characterized by ovulatory dysfunction, menstrual irregularity, infertility, hirsutism, obesity and insulin resistance. Fifty four women who consulted for hirsutism, menstrual irregularity or infertility were studied. Twenty four subjects presented normal menstruations and 30 oligoamenorrhea. Body weight was normal in 55.5% of patients and either overweight or obesity in 44.5% of them. A history of familiar diabetes type II was present in 59.3% of women. Total testosterone, free androgen index, basal insulinemia and post oral ingestion of glucose 75 g and HOMA were abnormally high in 20.4%, 40.7%, 9.3%, 50% and 30.6% of the cases respectively. Only 1 patient had glucose intolerance and there was no case of diabetes mellitus. There were not clinical or biochemical significant differences between hyperandrogenic patients presented with normal or abnormal menstrual cycles. It can be concluded that cases of hyperandrogenism and normal menses present the same physiopathology as cases of polycystic ovary syndrome with oligoamenorrhea
Palabras clave : Policystic ovary syndrome; hyperandrogenism; insulin resistance; hirsutism.