Revista chilena de nutrición
versión On-line ISSN 0717-7518
SANHUEZA C, Julio; NIETO K, Susana y VALENZUELA B., Alfonso. CONJUGATED LINOLEIC ACID: A TRANS ISOMER FATTY ACID POTENTIALLY BENEFICIAL. Rev. chil. nutr. [online]. 2002, vol.29, n.2, pp. 98-105. ISSN 0717-7518. doi: 10.4067/S0717-75182002000200004.
Conjugated linoleic acid (CLA) is a type of isomeric trans fatty acid that has been demonstrated to have diverse health beneficial effects. The most common naturally existing structural form of CLA is the 9c (cis), 11t (trans) isomeric configuration. CLA, which is commonly found in the tissues and/or secretions (i.e., milk) of ruminants, is formed from the isomerization of linoleic acid by the ruminal bacteria Butyrivibrio fibrisolvens. CLA may also be synthesized, in both ruminants and non ruminants, by desaturation of vaccenic acid (18:1, 11t) at the intestinal tract and/or the at liver of these animals. Daily ingestion of CLA in humans highly variable (0.5g/day-1.5g/day), pending on the individual and the country nutritional habits, and on the amount of meat, milk and milk-derived products consumed. Different biological and nutritional properties have been described for CLA, the most relevant being related to its hipocholesterolemic, antiatherogenic and immuno-stimulant action, the protective action against certain types of cancer, and its antioxidant and body-weight reduction effects ascribed.for the isomeric fatty acid. However, the definitive confirmation of these health beneficial effects needs more experimental and clinical evidences supporting these actions. Meanwhile, diverse products containing CLA are now offered at the retail market with increasing success, especially those preparations claiming body weight reduction properties for the isomeric fatty acid
Palabras clave : Conjugated linoleic acid; trans isomers; polyunsaturated fatty acids and health; ruminal Butyrivibrio fibrisolvens.