Revista chilena de infectología
versión ISSN 0716-1018
MOYA, Yanneth; BERNAL, Fernando; ROJAS, Eliana y BARTHEL, Elizabeth. Pharmaceutical follow up of antirretroviral treatment in outpatients. Rev. chil. infectol. [online]. 2012, vol.29, n.4, pp. 412-419. ISSN 0716-1018. doi: 10.4067/S0716-10182012000400008.
Adherence to antiretroviral therapy is key contributor to decreasesing morbidity and mortality from HIV/ AIDS infection. However, it is affected by treatment-related factors including the multiple adverse reactions and interactions arising from chronic polypharmacy. In order to determine drug-related problems, 66 outpatients from Hospital Carlos Van Buren on antiretroviral therapy were monitored. 100 % had medication-related problems and 46.1% of those problems were related to the safety of the therapy. Hypertriglyceridemia associated to the combined use of both nucleoside reverse transcriptase inhibitor and a non-nucleoside reverse transcriptase inhibitor was the most frequent adverse reaction. Results show that pharmacological monitoring of patients on antiretroviral treatment is necessary for the early identification of drug-related problems and for the proposal of alternatives that promote therapeutic safety and efficacy.
Palabras clave : Pharmaceutical care; pharmacist-managed; HIV medication.