SciELO - Scientific Electronic Library Online

 
vol.26 número3Caracterización de factores de virulencia y susceptibilidad antimicrobiana en cepas de Plesiomonas shigelloides aisladas de pacientes con diarrea aguda en Cuba índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Revista chilena de infectología

versión impresa ISSN 0716-1018

Resumen

GAITAN C, Sandra L; ESPINAL M, Paula A  y  GRUPO DE INVESTIGACION EN RESISTENCIA BACTERIANA, REGION CARIBE. Molecular characterization of extended-spectrum ß-lactamases-producing Escherichia coliand Klebsiella pneumoniae in hospitals of the Caribean Region, Colombia. Rev. chil. infectol. [online]. 2009, vol.26, n.3, pp. 239-246. ISSN 0716-1018.  http://dx.doi.org/10.4067/S0716-10182009000400006.

ESBL-producing in Enterobacteriaceae, is the main resistance mechanism to extended spectrum cephalosporin and monobactams. Seventy isolates collected of hospitals in four cities of the Colombian Caribean, were characterized to ESBL production and metalo-ß-lactamases by microbiological test. The ß-lactamases characterization were performed by IEF and RPC; genotyping by PFGE. Results evidenced the ESBL production at four cities with more frequency in Klebsiella pneumoniae isolated from UCI. The ß-lactamases present in Escherichia coli and in K. pneumoniae contributed co-resistance to different antibiotic families. Enzymes were detected with resistance to cephalosporin and carbapenems, suggesting presence of carbapenemases. Polyclonal isolates noticed, neither demonstrated presence of endemic strains nor association with epidemic outbreak. It is evident the importance to combine clinical, microbiological and molecular information to surveillance the prevalence and evolution of these enzymes in these hospitals.

Palabras clave : Escherichia coli; Klebsiella pneumoniae; ß-lactamases; ESBL; Colombia.

        · resumen en Español     · texto en Español     · pdf en Español