Revista chilena de infectología
versión impresa ISSN 0716-1018
APT B, Werner et al. Guidelines for chagas disease: Part IV. Chagas disease in immune compromissed patients. Rev. chil. infectol. [online]. 2008, vol.25, n.4, pp. 289-292. ISSN 0716-1018. doi: 10.4067/S0716-10182008000400008.
A summary of different kind of immune supressed hosts and the importance of Tryponosoma cruzi infection in this group of patients is presented. Then, most relevant aspects of immune compromised host-parasite interaction are analyzed such as the moment of acquiring the infection, immune compromise level, mechanisms of acquisition the infection and geographic region. Clinical features of primary infection and reactivation of infection in chronic Chagasic patients are described making especial emphasis in solid organ transplant and BMT. Chagas disease in AIDS patients is discussed including its treatment, follow up, monitoring the immune compromise level and prophylaxis
Palabras clave : Chagas disease; american Trypanosomiasis; immune compromised host; treatment.