Revista chilena de infectología
versión impresa ISSN 0716-1018
BERMEJO, Joaquín et al. High relationship between ciprofloxacin use and prevalence of ESBL Klebsiella pneumoniae. Rev. chil. infectol. [online]. 2006, vol.23, n.4, pp. 316-320. ISSN 0716-1018. http://dx.doi.org/10.4067/S0716-10182006000400004.
Background: To assess the relationship between ciprofloxacin use and the prevalence of extended spectrum betalactamases (ESBL) Klebsiella pneumoniae. Patients and Methods: Semestral mean values regarding use of antibiotic and prevalence of ESBL Kp were compared during 9 semesters using linear regression and coefficient of correlation. Results: The only statistically significant correlation was ciprofloxacin use and ESBL(+) K. pneumoniae prevalence, with a coefficient of correlation of 0.86 and p = 0.0027 using linear regression. Conclusions: Ciprofloxacin use must be taking into account when considering infection control programs due to high prevalence rates of ESBL(+) K. pneumoniae in the hospital setting
Palabras clave : Klebsiella pneumoniae; extended spectrum betalactamases; ciprofloxacin.