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Revista chilena de pediatría
versión impresa ISSN 0370-4106
VERDECIA C, C. Caridad; NARANJO U, Alfredo; RIVERA L, Katia y MARCANO S, Luis E. Thoracic neuroblastoma in adolescence: Clinical case. Rev. chil. pediatr. [online]. 2012, vol.83, n.2, pp.170-174. ISSN 0370-4106. http://dx.doi.org/10.4067/S0370-41062012000200008.
Neuroblastoma is predominantly a tumor of early childhood, most cases occur in children under 5 years old. It originates in the adrenal gland and paravertebral ganglion cells (neural crest-derived), being the most common an extracranial solid tumor in children. It is characteristic a spontaneous regression, However in some cases it shows progression and dissemination to other organs. Objetive: To show a neuroblastoma in adolescence, with poor response to chemotherapy and radiotherapy, requiring surgery treatment. Clinical case: A 16 y.o. Female patient, previously asymptomatic, who after a body temperature rise up to 39 ° C, was found to have a tumor in the right hemithorax. Biopsy was compatible with neuroblastoma. Surgical removal of a large 20 x 19 cm tumor was achieved, the only complication presented 10 days postop was recurrent pneumothorax. Conclusion: Despite little or no response to standard treatment, surgical resection of this large tumor achieved complete remission for this patient.
Palabras clave : Neuroblastoma chest; adolescence; ganglion cells; suprarrenal.