Revista chilena de pediatría
versión ISSN 0370-4106
MENENDEZ A, Marcela; RUMIE C, Karime y GARCIA B, Hernán. Induction of puberty in Turner's Syndrome. Rev. chil. pediatr. [online]. 2011, vol.82, n.5, pp. 432-438. ISSN 0370-4106. doi: 10.4067/S0370-41062011000500009.
Turner's Syndrome is the most frequent cause of female hypogonadism. Puberty must be pharmacologically induced in over 80% of these girls. Induction must be completed in a manner closest to physiology as possible. It is recommended that this induction be initiated at age 12 y.o. with natural estrogens (17 beta estradiol) in low dosage, equivalent to 1/10 a 1/8 of substitution dose, increasing stepwise and adding, after two years, a progestin to generate a menstruation. This revision shows various proposed schemes, as well as therapeutic alternatives available in Chile.
Palabras clave : Turner; puberty; hypogonadism.