Revista chilena de pediatría
versión impresa ISSN 0370-4106
TORDECILLA C, JUAN; VEGA G, ALVARO y TORDECILLA F, ROCÍO. Transient Childhood Erythroblastopenia: Three Cases and a Literature Review. Rev. chil. pediatr. [online]. 2009, vol.80, n.6, pp. 539-544. ISSN 0370-4106. doi: 10.4067/S0370-41062009000600007.
Transient childhood erythroblastopenia is a benign hematological condition, characterized by non-regenerative anemia and transient marrow aplasia. It is seen among post-viral infected children 1 through 14 years of age. Incidence is 4 in 100,000, and recovery is shown in 2-4 weeks. Objective: Three cases are presented, as a reminder due to low incidence, limited national literature and need for review of this subject. Clinical cases: Three patients, 1-4 years old, with similar symptoms including severe anemia, reticulocytopenia, and myelogram showing erythroblastopenia (2 cases) and one in recovery phase. No infectious etiology was identified. Hemogram, reactive protein C, hepatic and renal function studies, myelogram, bone marrow parvovirus B19 PCR, and Epstein-Barr IgM. Conclusions: Our experience is similar to that shown in the literature, with unidentified etiology, benign course, and emphasize on the differential diagnosis from congenital hypoplastic anemia.
Palabras clave : Transient erythroblastopenia of childhood; anemia; congenital hypoplastic anemia.