Revista chilena de pediatría
versión impresa ISSN 0370-4106
HERRERA V., José M. et al. Treatment progress and follow up of hepatoblastoma, an analysis of 9 children. Rev. chil. pediatr. [online]. 2002, vol.73, n.1, pp. 43-50. ISSN 0370-4106. http://dx.doi.org/10.4067/S0370-41062002000100008.
Hepatoblastoma is the commonest malignant liver tumour in children. Complete surgical excision is required to achieve a cure. Aim: An analysis of survival, clinical presentation, demography, adjuvent chemotherapy, surgical techniques, alphafoetoprotein levels and nutritional status in children with hepatoblastoma. Patients and Method: 9 children were followed up between may 1997 and december 2000. Results: the mean age at diagnosis was 24 months, all had a palpable abdominal mass and elevated alphafoetoprotein levels. They received pre and postoperative chemotherapy. Surgical resections were accomplished with negative margins. There was no operative mortality. One patient relapsed after 9 months and died 6 months later, the 3 year DFS was 89%. The childrens weight returned to the normal percentiles after tumour resection. Conclusions: A multidisciplinary team, early evaluation and specialized surgical approach are the basis for successful therapy in hepatoblastoma
Palabras llave : hepatoblastoma; children; alphafoetoprotein level; tumour.