Revista chilena de pediatría
versión impresa ISSN 0370-4106
The Hutchinson-Gilford syndrome or progeria is an uncommon disease. Its clinical manifestations are evident by the first or second year of life and are characterized by a general appearance of premature aging. Most cases are sporadic and an autosomal dominant inheritance has been suggested arising by a de novo mutation. It should be considered in the differential diagnosis of premature aging, along with other syndromes described in the literature. We present a review of progeria with special emphasis on diagnostic methods
Palabras llave : progeria; Hutchinson-Gilford syndrome; inheritance; progeroid syndromes.