Revista médica de Chile
versión impresa ISSN 0034-9887
MIRANDA C, Marcelo; TORRES T, Juan Pablo; LARRANAGA L, Carmen y ACUNA L, Guillermo. Meningomyelitis associated with infection by human herpes virus 7: Report of two cases. Rev. méd. Chile [online]. 2011, vol.139, n.12, pp. 1588-1591. ISSN 0034-9887. http://dx.doi.org/10.4067/S0034-98872011001200008.
Human herpesvirus 7 (HHV-7) may cause encephalomyelitis in immune competent adults. We report two patients infected by the virus. A 34-year-old male presenting with paraparesis and a sensitive deficiency located in D6 dermatome. Cerebrospinal fluid had 35 white blood cells per mm3 and 75 mg protein per dl. A PCR-microarray examination was positive for HHV-7. The patient was treated with prednisolone and ganciclovir with full recovery. A 27-year-old male presenting with headache, fever and diarrhea. Cerebrospinal fluid analysis showed 160 cells per mm3 and 75 mg protein per dl. Viral RNA detection was positive for HHV-7. The patient was managed with analgesia and rest and was discharged with the diagnosis of viral meningitis. Our communication supports the notion that HHV-7 may be considered as pathogen factor in humans, even in immune competent ones.
Palabras clave : Encephalomyelitis; Herpesvirus 7, human; Meningitis, viral.