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Revista médica de Chile

versión impresa ISSN 0034-9887

Resumen

LINCOPAN S, Anya; VALENCIA M, Yenny; CARRASCO L, Cristian  y  BARRAZA O, Ximena. Myeloid sarcoma: Report of one case with trisomy 11. Rev. méd. Chile [online]. 2011, vol.139, n.7, pp. 914-916. ISSN 0034-9887.  http://dx.doi.org/10.4067/S0034-98872011000700013.

Myeloid sarcoma is a form of extra-medullary myeloid neoplasia. Cytogenetic characterization is hampered in the absence of invasion to the bone marrow, origin of cells that are usually studied in cytogenetic studies. We report a 13years old mole presenting with a mass in the right shoulder. A biopsy of the tumor disclosed a Myeloid Sarcoma. A conventional cytogenetic study of a bone marrow aspirate did not show t (8;21) translocation. A fluorescent in situ hybridization (FISH) performed in the paraffin embedded biopsy of the tumor, detected a chromosome 11 trisomy.

Palabras clave : Chromosome 11 trisomy; FISH antifreeze proteins; Sarcoma, myeloid.

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