Revista médica de Chile
versión ISSN 0034-9887
LINCOPAN S, Anya; VALENCIA M, Yenny; CARRASCO L, Cristian y BARRAZA O, Ximena. Myeloid sarcoma: Report of one case with trisomy 11. Rev. méd. Chile [online]. 2011, vol.139, n.7, pp. 914-916. ISSN 0034-9887. doi: 10.4067/S0034-98872011000700013.
Myeloid sarcoma is a form of extra-medullary myeloid neoplasia. Cytogenetic characterization is hampered in the absence of invasion to the bone marrow, origin of cells that are usually studied in cytogenetic studies. We report a 13years old mole presenting with a mass in the right shoulder. A biopsy of the tumor disclosed a Myeloid Sarcoma. A conventional cytogenetic study of a bone marrow aspirate did not show t (8;21) translocation. A fluorescent in situ hybridization (FISH) performed in the paraffin embedded biopsy of the tumor, detected a chromosome 11 trisomy.
Palabras clave : Chromosome 11 trisomy; FISH antifreeze proteins; Sarcoma, myeloid.