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Revista médica de Chile
versión impresa ISSN 0034-9887
ALAMINOS G, PILAR; MENDUINA G, MANUEL JESÚS y DE LA CHICA RUIZ-RUANO, RAFAEL. Prosthetic valve thrombosis in a patient with antiphospholipid syndrome: Report of one case. Rev. méd. Chile [online]. 2010, vol.138, n.3, pp.330-333. ISSN 0034-9887. http://dx.doi.org/10.4067/S0034-98872010000300011.
Primary antiphospholipid syndrome (APS) is a thrombophilic disorder not associated with connective tissue diseases or with autoimmune diseases. We report a 39-year-old female with a mechanical prosthetic mitral valve and a primary antiphospholipid syndrome. Anticoagulation with warfarin was changedfor tinzaparine. Four days after the change, the patients was admitted in cardiogenic shock. A transesophageal echocardiogram showed a mass in the prosthetic valve suggestive of prosthetic thrombosis. The patient required two valve replacements due to thrombosis. Her anticardiolipin antibody titers were 84 UPL. She was discharged with a coagulation international normalized ratio of three.
Palabras clave : Antiphospholipid syndrome; Heart valve prosthesis; Thrombosis.