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Revista médica de Chile
versión impresa ISSN 0034-9887
CASTRO, Lorena et al. Accomodation process: ABO-incompatible liver transplantation. Report of one case. Rev. méd. Chile [online]. 2009, vol.137, n.8, pp.1061-1065. ISSN 0034-9887. http://dx.doi.org/10.4067/S0034-98872009000800010.
We report a 33 year-old female with a diagnosis of halothane-induce fulminant hepatic failure who was subjected to a liver transplant with an ABO-incompatible graft. The patient received a therapeutic protocol that included total plasma exchange, splenectomy and quadruple immunosuppression. After 5 years, the patient remains asymptomatic and with normal liver enzymes, while she has been treated with low dose of immunosuppressive drugs. This case demonstrates an example of how the immunological process of accomodation opens the possibility of using ABO-incompatible organs as a definitive grafts.
Palabras clave : ABO Blood-group system; Allergy and Immunology; Liver transplantation.