Revista médica de Chile
versión impresa ISSN 0034-9887
SOLER, Bernardita; GODOY, Jaime y MELLADO, Patricio. Treatment of refractory status epilepticus with topiramate. Report of three cases. Rev. méd. Chile [online]. 2009, vol.137, n.7, pp. 936-939. ISSN 0034-9887. http://dx.doi.org/10.4067/S0034-98872009000700012.
Refractory status epilepticus is a catastrophic illness of the central nervous system, with a mortality rate that reaches 50%. We report three patients admitted with refractory status epilepticus: a 24 year-old male that discontinued antiepileptic medications, a 46 year-old male with a focal epilepsy secondary to an encephalitis that discontinued medications due to gastrointestinal problems and a 59 year-old male with an ischemic encephalopathy AH were treated with topiramate, delivered through a nasogastric tube with a good response.
Palabras llave : Anticonvulsants; Status epilepticus; Topiramate.