Revista médica de Chile
versão impressa ISSN 0034-9887
ROJAS A, Gonzalo; GONZALEZ G, Néstor; VENABLES G, Cristián e ARAOS H, Daniel. Gran versus host disease with oral involvement: Report of one case. Rev. méd. Chile [online]. 2008, vol.136, n.12, pp. 1570-1573. ISSN 0034-9887. doi: 10.4067/S0034-98872008001200010.
Gran versus Host Disease (GVHD) is a common complication in allogenic bone marrow transplants and in some cases, it involves the oral mucosa. Therefore, the appropriate diagnosis and timely treatment is essential to prevent ¡ocal complications which interfere with normal oral functions and facilitate infection spread. We report a 17 years old woman with GVHD associated to ¡ichenoid and ulcerative ¡essions in the oral mucosa, which responded to the topical administration of a 0.1% tacrolimus ointment.
Palavras-chave : Bone marrow transplantation; Gran us host disease; Tacrolimus.