Revista médica de Chile
Print version ISSN 0034-9887
RIOS S, Lorena; SAPUNAR Z, Jorge and ROA E, Iván. Primary hyperparathyroidism with severe skeletal involvement in one patient with parathyroid carcinoma. Rev. méd. Chile [online]. 2005, vol.133, n.1, pp. 77-81. ISSN 0034-9887. doi: 10.4067/S0034-98872005000100010.
Parathyroid carcinoma is an uncommon cause of primary hyperparathyroidism; however, when this condition is severe, cancer must be suspected. We report on a 28-year-old male with severe hypercalcemia, cachexia, acute pancreatitis, urolithiasis, anemia and a severe skelletal involvement with multiple fractures. The patient had a 4-cm parathyroid tumor, that was surgically excised, along with the ipsilateral thyroid lobe. During the postoperative period, he had a severe and prolonged hungry bone syndrome, with a slow recovery of fractures, with functional and anatomical sequelae in the extremities. PTH levels were adequate for the serum calcium during the 16 months of follow-up (Rev Méd Chile 2005; 133; 77-81)
Keywords : Hypercalcemia; Hyperparathyroidism; Parathyroid neoplasms.